Review Article: Review: T helper 17 cells: Their role in glomerulonephritis
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Review Article Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis
The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and extracellular bacterial infections, has profoundly revolutionized our current understanding of T cell-mediated responses in autoimmune diseases, including multiple sclerosis (MS). Indeed, recent data demonstrate the pathogenic role of Th17 cells in autoimmune disorders. In particular, studies in MS and ...
متن کاملthe role of interleukin-23 in stability of in vitro t helper-17 cells.
interleukin (il)-17-producing t helper (th)-17 cells have recently been explained as a distinct population of cd4+ t cells which play an important role in immunity against infectious agents. establishment of persistent phenotype of th17 cells and recognition of lineage-deviating factors are of most attractive goals in modern researches in immunology. although il-6 and tgf-β are freque...
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Chick embryos are a great historical research model in basic and applied sciences. Along with other animal models, avian and specifically chicken embryo has been attended, as well. Avian fertilized eggs as a natural bioreactor are an efficient tool for producing recombinant proteins and vaccines manufacturing. Due to the limitations of birds' eggs for viral replication, avian stem cells culture...
متن کاملP 51: The Role of T Helper 17 in Pathogenesis of Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) which causes demyelination of the nerve fibers. The etiology of this disease is not well understood but it is believed that T helpers play a central role in MS. Numerous findings support the view that Th17 cells play an essential role in pathogenesis of MS and IL-17 secreting T (Th17) cells have a role in infla...
متن کاملThe role-playing autoantibodies in autoimmune thyroid diseases and their extra-thyroidal manifestations: review article
The presence of the antibodies against the main thyroid antigens, which include thyroid peroxidase (TPO) or microsomal antigen, thyroglobulin (Tg) as well as thyrotropin receptor or Thyroid Stimulating Hormone Receptor (TSH-R), is a hallmark and symbol of the autoimmune thyroid diseases (AITDs) as one of the most common autoimmune diseases (AD) around the world. The prevalence of the thyroid pe...
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ژورنال
عنوان ژورنال: Nephrology
سال: 2010
ISSN: 1320-5358
DOI: 10.1111/j.1440-1797.2010.01343.x